Every article, newest first.
In the INFRONT-3 phase 3 trial, published in October 2026 in Alzheimer's & Dementia, latozinemab raised progranulin levels in people with frontotemporal dementia from GRN mutations, but didn't slow the disease over…
A review published Oct. 29, 2026, in The Lancet explains irritable bowel syndrome and related gut-brain disorders, which affect 20% of the world's population, and what helps: education, diet, fiber, targeted drugs…
A study of 10,375 Europeans followed for up to 18 years, published in October 2026 in Alzheimer's & Dementia, found that poorer hearing, loneliness and weaker memory go together, but found little…
A meta-analysis of 21 studies estimated the global prevalence of frontotemporal dementia, a leading cause of dementia before age 65, at 30 cases per 100,000 people, with extreme differences between studies.
In a study of 136 older adults published Oct. 30, 2026, in GeroScience, delayed recall on a face-name memory test told apart people with mild cognitive impairment about as well as the…
A network meta-analysis of thirty-eight randomized trials, published Oct. 20, 2026, in PeerJ, found that moderate exercise doses, about 300 to 1,000 MET-minutes a week, gave the most reliable gains in executive…
A preregistered analysis of 40 brain-imaging datasets with 2,175 participants, published Oct. 28, 2026, in Nature, found that common measures of how well people reframe emotions didn't agree with each other or…
In the HEALEY ALS Platform Trial, 325 participants took DNL343 or placebo for 24 weeks. The drug, which targets the cell's integrated stress response, did not slow loss of function or improve…
A meta-analysis published Oct. 26, 2026, in GeroScience compared dementia risk scores. CAIDE did best, with an accuracy (AUC) of 0.74 to 0.76, especially in middle-aged people followed for longer; the original…
A network meta-analysis of randomized trials found that multicomponent interventions, which combine several types of support, were the only approach that significantly reduced burden in family caregivers of people with dementia.
A study published Oct. 1, 2026, in JAMA Network Open estimated that 74.5% of former NFL players who died between 2008 and 2023 had chronic traumatic encephalopathy, after correcting for the bias…
A study of 127 patient-caregiver pairs in China, published in October 2026 in Alzheimer's & Dementia, linked caregivers' positive view of caregiving to better 18-month outcomes in cognition, daily function and quality…
A meta-analysis of the Brain Injury Guidelines, a tool to sort head injury patients with findings on a scan, found a sensitivity of 98.2% to 98.7% for ruling out deterioration, surgery and…
In a randomized trial published Oct. 28, 2026, in the American Journal of Clinical Nutrition, older adults who took blueberry powder for three months had more blood flow in a brain area…
Pooling double-blind trials in adults with depression, escitalopram and amitriptyline lengthened the QTc interval, a heart rhythm measure, more than placebo. Antidepressants were not linked to more early major heart events.
In a Medicare study published Oct. 1, 2026, in JAMA Network Open, people with dementia who had more annual wellness visits in the previous 3 years were more likely to start a…
A genetic study of more than 2 million people published Oct. 28, 2026, in Nature identified 118 Alzheimer's risk regions in a multi-ancestry analysis, plus 9 more in specific ancestries, 48 of…
A study published Oct. 27, 2026, in Nature Medicine found that in ALS, more T cells in the spinal fluid went with slower progression, while more activated T cells in the blood…
A Korean study of 116,563 people with cognitive impairment, published Oct. 24, 2026, in GeroScience, linked aerobic activity to lower death rates, especially from pneumonia (hazard ratio 0.554 with high activity), even…
An analysis of 1.32 billion T cell clones from 798 people with cancer and 5052 without, published in November 2026 in Aging Cell, found that T cell receptor diversity declines faster after…
