Guides: health questions, answered with evidence
Each guide answers one question people ask all year, with every study we have covered on it and its A–E evidence grade.
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Longevity drugs: the pipeline tracker
As of Nov. 3, 2026, the FDA has not approved any drug to treat aging itself; candidates such as metformin and rapamycin are still being tested in human trials registered on ClinicalTrials.gov (sources: FDA, ClinicalTrials.gov, checked Nov. 3, 2026).
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Supplements: does it work?
In the U.S., dietary supplements do not need FDA approval before they are sold, under the Dietary Supplement Health and Education Act of 1994 (source: FDA, checked Nov. 3, 2026).
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Aesthetic treatments compared
Botulinum toxin for frown lines has been FDA-approved since 2002, while many at-home devices are only FDA-cleared, which is a lower bar than approval (sources: FDA, checked Nov. 3, 2026).