Vaccines, infections and the aging immune system.
A multicenter study in Argentina, published in 2026 in Medicina (Buenos Aires), found whooping cough bacteria in only 1 of 391 adults with a recent cough, while viruses were common and hospitalization…
A CDC study published Oct. 1, 2026, in JAMA Network Open found that most typhoid and paratyphoid infections diagnosed in the US from 2016 to 2020 were not susceptible to ciprofloxacin, and…
A meta-analysis of forty-three studies, published Oct. 7, 2026, in Frontiers in Public Health, linked a history of smoking to higher odds of antibiotic-resistant infection (odds ratio 1.66), with most evidence from…
Analyzing 3.8 million blood immune cells from 1,828 people aged 19 to 97, researchers found that immune aging is not gradual: it shows bursts of change around age 40 and after 60,…
In an analysis of the Danish DAN-RSV trial, published in The Lancet Healthy Longevity in October 2026, RSV hospitalization was more than nine-fold higher in unvaccinated older adults with weakened immunity, and…
In a study of US veterans 50 and older, published Oct. 1, 2026, in JAMA Network Open, the mRNA-1345 RSV vaccine had an estimated effectiveness of 81.8% against RSV hospitalization in one…
A study published Oct. 28, 2026, in Nature found that neutrophils from people with lupus contain many abnormally spliced gene messages that produce new protein pieces. Twenty-one such pieces were found on…
In a phase 2b trial published in NEJM in October 2026, oral icotrokinra led to a clinical response at week 12 in 63% of people with ulcerative colitis at the highest dose…
In two trials published in NEJM in October 2026, monthly ianalumab lowered Sjögren's disease activity at week 48 slightly more than placebo, but patient-reported symptoms didn't improve more.
A study published Oct. 28, 2026, in Nature mapped 3.5 million blood immune cells from 1,042 people to show how DNA variants change which genes can be switched on in each cell…
An umbrella review of twenty-one reviews found that exercise may produce small reductions in the inflammation markers TNF-alpha and CRP in older adults and people with chronic disease, while effects on IL-6…
A meta-analysis of twenty-two reports, published Oct. 8, 2026, in Frontiers in Immunology, found that randomized trials don't show that exercise before a flu shot, or regular training, clearly improves antibody responses,…
In a US survey published Oct. 1, 2026, in JAMA Network Open, 27.9% of adults said they had misrepresented symptoms to a clinician to get antibiotics, most often for cold-like symptoms.
In a phase 1 trial published Oct. 28, 2026, in Science Translational Medicine, 45 healthy adults were infected with a weakened dengue virus. People's existing antibodies and T cells shaped how much…
In a randomized trial published Oct. 26, 2026, in the American Journal of Clinical Nutrition, healthy adults who ate 56 g of almonds a day had higher antibody levels against one flu…
