In the MILD-MT trial, published Oct. 23, 2026, in NEJM, 69.4% of people with a mild stroke from a large blocked artery had an excellent recovery at 90 days with clot removal vs. 50.0% with medicines alone, but procedure complications…
In the LATE-MT trial, published Oct. 23, 2026, in NEJM, removing the clot 24 to 72 hours after a large-artery stroke improved function at 90 days, but brain bleeding (4.8% vs. none) and deaths (6.0% vs. 1.8%) were higher.
A Cochrane review published Oct. 29, 2026, pooled 12 randomized trials with 1860 people and found no evidence that levodopa or dopamine agonists improve motor function after stroke. Serious side effects were similar with or without the drugs.