A Cochrane review of nine trials with 922 women found that mifepristone may reduce painful periods in endometriosis, but may cause hot flushes. Evidence for other progesterone receptor modulators was low or very low certainty.
A Cochrane review of nine trials with 922 women found that mifepristone may reduce painful periods in endometriosis, but may cause hot flushes. Evidence for other progesterone receptor modulators was low or very low certainty.
In a cohort of 19,903 women with endometriosis and 79,612 matched women without it in Beijing, endometriosis was linked to a higher risk of cardiovascular disease (hazard ratio 1.69), with a similar link at younger and older ages.
In a cohort of 19,903 women with endometriosis and 79,612 matched women without it in Beijing, endometriosis was linked to a higher risk of cardiovascular disease (hazard ratio 1.69), with a similar link at younger and older ages.
In the MIRA2 trial, published Oct. 21, 2026, in The Lancet, women treated for heavy menstrual bleeding with endometrial ablation plus a levonorgestrel IUD needed a hysterectomy within 2 years in 4% of cases, vs. 10% with ablation alone.
In the MIRA2 trial, published Oct. 21, 2026, in The Lancet, women treated for heavy menstrual bleeding with endometrial ablation plus a levonorgestrel IUD needed a hysterectomy within 2 years in 4% of cases, vs. 10% with ablation alone.